In the metanarrative of Scripture, the entrance of sin into creation at the Fall is a pivotal event with cosmic implications. Thus, in seeking to interpret the natural world through the lens of Scripture, a correct understanding of the Fall and its effects on the physical creation is essential. Here we compile a review of the scriptural passages which describe these effects, with the goal of providing a concise and rigorous definition of the same. The relevant descriptive scriptural passages are assembled in four categories. Firstly, descriptive of creation in its original, pre-Fall state, highlighting the distinctions between that state and its present state. Secondly, descriptive of the Fall and subsequent Curse, focusing on the third chapter of Genesis. Thirdly, descriptive of creation in its present, post-Fall state, both in the Old and New Testaments. Fourthly, descriptive of the coming restoration of creation, understanding that creation will be restored to something akin to its original state. A definition of the effects of the Fall on the physical creation should include human death, predation (if not all animal death) at least in terrestrial and avian animals, physiological and behavioral changes in both plants and living creatures, and of the entire created order corruption.