Formerly many of the chemical elements were regarded as being without biological significance. However, an increasing number of both metals and non-metals in minute quantities (trace elements) in the soil and diets, have been shown to have profound effects on plant and animal life. These chemical and physiological studies show the remarkable and complicated interlocking of the functions of many elements. Such can hardly be attributed to chance or evolution, but rather to the direction of the infinitely wise and almighty Creator, who has purpose in all the materials of his Creation.