According to evolutionary thinking, adaptive genetic changes are the result of random (non-purposeful) mutations and natural selection. While creationists do not need to account for the assumed changes that turn microbes into people, our model certainly points to a considerable amount of adaptive change that has occurred within created kinds. The naturalistic mechanisms proposed by evolutionists appear woefully inadequate to account for these. A look at the immune system reveals several different enzymes that are used to edit DNA; one of them is activation-induced cytidine deaminase (AID). AID is involved in gene conversion, somatic hypermutation, and class-switch recombination in B lymphocytes. While each of these begins with AID converting a cytosine residue to a uracil residue, the different outcomes are a function of different proteins being recruited to process the lesion. Since the activity of AID could be disastrous if not kept in its proper place, it is well regulated and tightly controlled at many levels. The well-designed DNA editing function of AID and other proteins in the immune system give reason to believe that adaptive alleles in various populations have similarly arisen by the providence of God, the Great Designer, and not by the naturalistic mechanisms proposed by evolutionists.