Dr. Benjamin Rush (1745–1813) was a leading founding father of the United States of America. He received the best medical education available in his day. Dr. Rush patriotically served his new nation both in peacetime and war. As a pioneer in physical and mental health, he was respected on both sides of the Atlantic. Throughout his long and useful life, Rush was a devout Christian who treasured the Holy Scriptures as God’s Word. Much of the foundation for his medical and benevolent activities he learned from the first chapters of the book of Genesis, which he believed were composed of actual, historical people and events. This article examines the scientific and medical genius of Dr. Benjamin Rush and his Christian faith that guided his research and life.