Natural products phytochemistry, exemplified by the "bitter herbs", has served the medicinal needs of mankind since antiquity, and continues to do so in the present era. The appearance of pathogens resistant to existing pharmacology, notably to synthetic drugs, new diseases, and the continuing bane of cancers, cardiovascular diseases, endocrine dysfunctions, neurological disorders, immunopathology, etc. are stimulating renewed interest in possible biological sources of new therapeutic principles. Remarkably, biogenic alkaloids having no direct function in the metabolism or structure of the plants that manufacture them have highly specific molecular interactions in man (or his infectious pathogens and/or their vectors) and the agents which plague his food sources. Such interactions underlie their pharmacological (or pesticidal top10pharma.net) properties. These and related observations have significance to a creationist concept of their origin.