Some have claimed that modern genetic data is at odds with biblical history. Yet closer examination reveals that the opposite is true. In terms of the origin of humanity, genetic data support the fact that all humans alive today can trace their ancestry back to a single male and a single female. When evolutionary assumptions are discarded and actual observable mutation rates are used, the molecular clock indicates that those individuals lived within a biblical time frame. Analysis of the human mitochondrial data reveals three major mitochondrial lineages, which appear to point to the three daughters-in-law of Noah. The Y chromosome distribution pattern supports a single paternally based dispersion as expected by the Babel event. Yet many questions remain, even as genetic data accumulate and computers make modeling more accessible to those outside the traditional university setting. The time is ripe for productive creationist research to answer important questions about the genetic history of humans using the wealth of data and tools now at our disposal.