Present sources of energy for conversion of inorganic molecules to various organic molecules are given. Electrical discharges, used by Miller and Urey, are shown to be relatively minor ones, compared to the sun’s energy which is so effective in destroying organic compounds. Even though set up as a closed system, so as to force the reaction to the product side by selectively removing and accumulating the products, only slight amounts of various organic compounds, such as glycine, resulted. Quoting Hull as estimating the half-life of glycine as only about 30 days, 97% of it would be decomposed before reaching the earth. Considering the possible 3% which falls into the ocean, Hull concludes that ultraviolet radiation would decompose it in the upper 100 meters in a half-life of about 20 years. The physical chemist guided by proved principles of chemical thermo-dynamics and kinetics cannot offer any encouragement to the biochemist who needs an ocean full of organic compounds to form even lifeless coacervates. Miller’s experiment is an excellent one, scientifically-speaking, and when properly interpreted leads to the conclusion that life could certainly never originate spontaneously.