Evolution simply could not have occurred unless both the first and second laws of thermodynamics were violated many times. After explaining thermodynamics in non-mathematical language, relation of the first law to evolution, and relation of the second law to evolution, is given extensive consideration. Three arguments, which are often offered to “defend” the occurrence of evolution in spite of thermodynamics, are studied carefully. It is concluded that the first and second laws of thermodynamics overrule evolution.